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The α5 Nicotinic Acetylcholine Receptor Subunit Differentially Modulates α4β2(*) and α3β4(*) Receptors

Nicotine, the principal reinforcing compound in tobacco, acts in the brain by activating neuronal nicotinic acetylcholine receptors (nAChRs). This review summarizes our current knowledge regarding how the α5 accessory nAChR subunit, encoded by the CHRNA5 gene, differentially modulates α4β2(*) and α3...

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Bibliographic Details
Published in:Front Synaptic Neurosci
Main Authors: Scholze, Petra, Huck, Sigismund
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7744819/
https://ncbi.nlm.nih.gov/pubmed/33343327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnsyn.2020.607959
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