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The α5 Nicotinic Acetylcholine Receptor Subunit Differentially Modulates α4β2(*) and α3β4(*) Receptors

Nicotine, the principal reinforcing compound in tobacco, acts in the brain by activating neuronal nicotinic acetylcholine receptors (nAChRs). This review summarizes our current knowledge regarding how the α5 accessory nAChR subunit, encoded by the CHRNA5 gene, differentially modulates α4β2(*) and α3...

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Détails bibliographiques
Publié dans:Front Synaptic Neurosci
Auteurs principaux: Scholze, Petra, Huck, Sigismund
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7744819/
https://ncbi.nlm.nih.gov/pubmed/33343327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnsyn.2020.607959
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