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Cell Type-Specific Annotation and Fine Mapping of Variants Associated With Brain Disorders

Common genetic variants confer susceptibility to a large number of complex brain disorders. Given that such variants predominantly localize in non-coding regions of the human genome, there is a significant challenge to predict and characterize their functional consequences. More importantly, most av...

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Publicado en:Front Genet
Autores principales: Doostparast Torshizi, Abolfazl, Ionita-Laza, Iuliana, Wang, Kai
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7744805/
https://ncbi.nlm.nih.gov/pubmed/33343624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2020.575928
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