Cell-Type-Specific Proteogenomic Signal Diffusion for Integrating Multi-Omics Data Predicts Novel Schizophrenia Risk Genes

Accumulation of diverse types of omics data on schizophrenia (SCZ) requires a systems approach to model the interplay between genome, transcriptome, and proteome. We introduce Markov affinity-based proteogenomic signal diffusion (MAPSD), a method to model intra-cellular protein trafficking paradigms...

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Bibliografiske detaljer
Udgivet i:Patterns (N Y)
Main Authors: Doostparast Torshizi, Abolfazl, Duan, Jubao, Wang, Kai
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7518509/
https://ncbi.nlm.nih.gov/pubmed/32984858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.patter.2020.100091
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