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Reduced lifespan of erythrocytes in Dahl/Salt sensitive rats is the cause of the renal proximal tubule damage

We studied the mechanisms of anemia and the influence of anemia on renal pathology in Dahl/Salt Sensitive (Dahl/SS) rat, a model of cardio-renal-anemia syndrome. Erythrocyte lifespan was shortened and associated with decreased hemoglobin level in the Dahl/SS rats given high-salt diet. Serum haptoglo...

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Dettagli Bibliografici
Pubblicato in:Sci Rep
Autori principali: Manabe, Eri, Ito, Satoyasu, Ohno, Yoshiya, Tanaka, Toshiyuki, Naito, Yoshiro, Sasaki, Naoko, Asakura, Masanori, Masuyama, Tohru, Ishihara, Masaharu, Tsujino, Takeshi
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7744793/
https://ncbi.nlm.nih.gov/pubmed/33328561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-79146-9
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