TNFR1 and the TNFα axis as a targetable mediator of liver injury from stereotactic body radiation therapy

INTRODUCTION: Radiation therapy for the management of intrahepatic malignancies can adversely affect liver function. Liver damage has been associated with increased levels of inflammatory cytokines, including tumor necrosis factor alpha (TNFα). We hypothesized that an inflammatory state, characteriz...

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Bibliographic Details
Published in:Transl Oncol
Main Authors: Cousins, Matthew M., Morris, Emily, Maurino, Christopher, Devasia, Theresa P., Karnak, David, Ray, Dipankar, Parikh, Neehar D., Owen, Dawn, Ten Haken, Randall K., Schipper, Matthew J., Lawrence, Theodore S., Cuneo, Kyle C.
Format: Artigo
Language:Inglês
Published: Neoplasia Press 2020
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Original article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7744766/
https://ncbi.nlm.nih.gov/pubmed/33395747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tranon.2020.100950
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