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Inactivation of TMEM106A promotes lipopolysaccharide‐induced inflammation via the MAPK and NF‐κB signaling pathways in macrophages

Pattern recognition receptors, such as Toll‐like receptors (TLRs), play an important role in the host defense against invading microbial pathogens. Their activation must be precisely regulated, as inappropriate activation or overactivation of TLR signaling pathways may result in inflammatory disorde...

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Bibliographische Detailangaben
Veröffentlicht in:Clin Exp Immunol
Hauptverfasser: Zhang, X., Feng, T., Zhou, X., Sullivan, P. M., Hu, F., Lou, Y., Yu, J., Feng, J., Liu, H., Chen, Y.
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7744488/
https://ncbi.nlm.nih.gov/pubmed/33006758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cei.13528
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