Cynandione A attenuates lipopolysaccharide-induced production of inflammatory mediators via MAPK inhibition and NF-κB inactivation in RAW264.7 macrophages and protects mice against endotoxin shock

Cynanchum wilfordii has been traditionally used in eastern Asia for the treatment of various diseases such as gastrointestinal diseases and arteriosclerosis. Cynandione A (CA), an acetophenone, is one of major constituents from roots of C. wilfordii. In the present study, the anti-inflammatory activ...

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Detalhes bibliográficos
Publicado no:Exp Biol Med (Maywood)
Main Authors: Kim, Sung Hwan, Lee, Tae Hoon, Lee, Sang Min, Park, Ji Hae, Park, Keun Hyung, Jung, Mira, Jung, Hana, Mohamed, Mohamed Antar Aziz, Baek, Nam-In, Chung, In Sik, Kim, Jiyoung
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2014
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4935409/
https://ncbi.nlm.nih.gov/pubmed/25361770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1535370214558022
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