Cynandione A attenuates lipopolysaccharide-induced production of inflammatory mediators via MAPK inhibition and NF-κB inactivation in RAW264.7 macrophages and protects mice against endotoxin shock

Cynanchum wilfordii has been traditionally used in eastern Asia for the treatment of various diseases such as gastrointestinal diseases and arteriosclerosis. Cynandione A (CA), an acetophenone, is one of major constituents from roots of C. wilfordii. In the present study, the anti-inflammatory activ...

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Vydáno v:Exp Biol Med (Maywood)
Hlavní autoři: Kim, Sung Hwan, Lee, Tae Hoon, Lee, Sang Min, Park, Ji Hae, Park, Keun Hyung, Jung, Mira, Jung, Hana, Mohamed, Mohamed Antar Aziz, Baek, Nam-In, Chung, In Sik, Kim, Jiyoung
Médium: Artigo
Jazyk:Inglês
Vydáno: SAGE Publications 2014
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4935409/
https://ncbi.nlm.nih.gov/pubmed/25361770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1535370214558022
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