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New Insights Into Drug Discovery Targeting Tau Protein
Microtubule-associated protein tau is characterized by the fact that it is an intrinsically disordered protein due to its lack of a stable conformation and high flexibility. Intracellular inclusions of fibrillar forms of tau with a β-sheet structure accumulate in the brain of patients with Alzheimer...
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| Publicado en: | Front Mol Neurosci |
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| Autores principales: | , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Frontiers Media S.A.
2020
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7744460/ https://ncbi.nlm.nih.gov/pubmed/33343298 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2020.590896 |
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