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A Chemiluminescent Immunoassay for Osteocalcin in Human Serum and a Solution to the “Hook Effect”

A chemiluminescent immunoassay for human serum osteocalcin, or bone Gla protein, was established using a double-antibody sandwich model. Examination of the hook effect revealed that it was significantly reduced, and no hook effect was observed at an osteocalcin concentration of 4000 ng/mL. The estab...

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Detalhes bibliográficos
Publicado no:J Anal Methods Chem
Main Authors: Han, Shuang, Xue, Yifeng, Zhang, Junlan, Huang, Jianrong, Liu, Xiuxia, Yang, Yankun, Bai, Zhonghu, Wang, Chunxin
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7744234/
https://ncbi.nlm.nih.gov/pubmed/33376621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/8891437
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