Rapid process development of serum-free pseudorabies virus production with the Quality by Design approach

This study described a successful application of the Quality by Design (QbD) approach to pseudorabies virus (PRV) production process development in a fixed-bed bioreactor using the serum-free medium (SFM). The innovated tube-fixed-bed bioreactor was used as a scale-down model of the fixed-bed biorea...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Cytotechnology
Hauptverfasser: Nie, Jianqi, Sun, Yang, Han, Fei, Yang, Yankun, Liu, Xiuxia, Liu, Chunli, Li, Ye, Bai, Zhonghu
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer Netherlands 2020
Schlagworte:
Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7193014/
https://ncbi.nlm.nih.gov/pubmed/32086694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10616-020-00377-9
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