Autotaxin Inhibition Reduces Cardiac Inflammation and Mitigates Adverse Cardiac Remodeling After Myocardial Infarction

OBJECTIVE: Acute myocardial infarction (AMI) initiates pathological inflammation which aggravates tissue damage and causes heart failure. Lysophosphatidic acid (LPA), produced by autotaxin (ATX), promotes inflammation and the development of atherosclerosis. The role of ATX/LPA signaling nexus in car...

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Detalhes bibliográficos
Publicado no:J Mol Cell Cardiol
Main Authors: Tripathi, Himi, Al-Darraji, Ahmed, Abo-Aly, Mohamed, Peng, Hsuan, Shokri, Elica, Chelvarajan, Lakshman, Donahue, Renee, Levitan, Bryana M., Gao, Erhe, Hernandez, Gabriela, Morris, Andrew J., Smyth, Susan S., Abdel-Latif, Ahmed
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7744112/
https://ncbi.nlm.nih.gov/pubmed/33017574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2020.09.011
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