Downregulation of the tyrosine degradation pathway extends Drosophila lifespan

Aging is characterized by extensive metabolic reprogramming. To identify metabolic pathways associated with aging, we analyzed age-dependent changes in the metabolomes of long-lived Drosophila melanogaster. Among the metabolites that changed, levels of tyrosine were increased with age in long-lived...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:eLife
Main Authors: Parkhitko, Andrey A, Ramesh, Divya, Wang, Lin, Leshchiner, Dmitry, Filine, Elizabeth, Binari, Richard, Olsen, Abby L, Asara, John M, Cracan, Valentin, Rabinowitz, Joshua D, Brockmann, Axel, Perrimon, Norbert
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2020
Assuntos:
Genetics and Genomics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7744100/
https://ncbi.nlm.nih.gov/pubmed/33319750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.58053
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados