Mapping cisplatin-induced viscosity alterations in cancer cells using molecular rotor and fluorescence lifetime imaging microscopy

Significance: Despite the importance of the cell membrane in regulation of drug activity, the influence of drug treatments on its physical properties is still poorly understood. The combination of fluorescence lifetime imaging microscopy (FLIM) with specific viscosity-sensitive fluorescent molecular...

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Dades bibliogràfiques
Publicat a:J Biomed Opt
Autors principals: Shimolina, Liubov E., Gulin, Alexander A., Paez-Perez, Miguel, López-Duarte, Ismael, Druzhkova, Irina N., Lukina, Maria M., Gubina, Margarita V., Brooks, Nicolas J., Zagaynova, Elena V., Kuimova, Marina K., Shirmanova, Marina V.
Format: Artigo
Idioma:Inglês
Publicat: Society of Photo-Optical Instrumentation Engineers 2020
Matèries:
Imaging
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7744042/
https://ncbi.nlm.nih.gov/pubmed/33331150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1117/1.JBO.25.12.126004
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