Mapping cisplatin-induced viscosity alterations in cancer cells using molecular rotor and fluorescence lifetime imaging microscopy

Significance: Despite the importance of the cell membrane in regulation of drug activity, the influence of drug treatments on its physical properties is still poorly understood. The combination of fluorescence lifetime imaging microscopy (FLIM) with specific viscosity-sensitive fluorescent molecular...

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Udgivet i:J Biomed Opt
Main Authors: Shimolina, Liubov E., Gulin, Alexander A., Paez-Perez, Miguel, López-Duarte, Ismael, Druzhkova, Irina N., Lukina, Maria M., Gubina, Margarita V., Brooks, Nicolas J., Zagaynova, Elena V., Kuimova, Marina K., Shirmanova, Marina V.
Format: Artigo
Sprog:Inglês
Udgivet: Society of Photo-Optical Instrumentation Engineers 2020
Fag:
Imaging
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7744042/
https://ncbi.nlm.nih.gov/pubmed/33331150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1117/1.JBO.25.12.126004
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