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Pervasive Selection against MicroRNA Target Sites in Human Populations

MicroRNA target sites are often conserved during evolution and purifying selection to maintain such sites is expected. On the other hand, comparative analyses identified a paucity of microRNA target sites in coexpressed transcripts, and novel target sites can potentially be deleterious. We proposed...

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Detalhes bibliográficos
Publicado no:Mol Biol Evol
Main Authors: Hatlen, Andrea, Marco, Antonio
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7743725/
https://ncbi.nlm.nih.gov/pubmed/32585012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/msaa155
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