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Effect of Nutritional Stress on the Expression of Sirtuin Gene Family

The sirtuin (SIRT) proteins are a highly conserved family of NAD+-dependent deacetylases that regulate histones as well as non-histone proteins. Seven sirtuin genes have been identified (SIRT1 to SIRT7) in mammals. SIRT1, SIRT6, and SIRT7 are primarily localized in the nucleus. SIRT2 is localized ma...

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Détails bibliographiques
Publié dans:Innov Aging
Auteurs principaux: Zhang, Xiaomin, Ameer, Fathima, Crane, Jasmine, Azhar, Gohar, Wei, Jeanne
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7740342/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/geroni/igaa057.407
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