Dysregulation of Insulin-Linked Metabolic Pathways in Alzheimer’s Disease: Co-Factor Role of Apolipoprotein E ɛ4

BACKGROUND: Brain insulin resistance and deficiency are well-recognized abnormalities in Alzheimer’s disease (AD) and likely mediators of impaired energy metabolism. Since apolipoprotein E (APOE) is a major risk factor for late-onset AD, it was of interest to examine its potential contribution to al...

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Vydáno v:J Alzheimers Dis Rep
Hlavní autoři: Robbins, James, Busquets, Oriol, Tong, Ming, de la Monte, Suzanne M.
Médium: Artigo
Jazyk:Inglês
Vydáno: IOS Press 2020
Témata:
Research Report
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7739986/
https://ncbi.nlm.nih.gov/pubmed/33344887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/ADR-200238
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