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Computational Investigation of the Binding Dynamics of Oligo p-Phenylene Ethynylene Fluorescence Sensors and Aβ Oligomers

Amyloid protein aggregates are pathological hallmarks of neurodegenerative disorders such as Alzheimer’s (AD) and Parkinson’s (PD) diseases and are believed to be formed well before the onset of neurodegeneration and cognitive impairment. Monitoring the course of protein aggregation is thus vital to...

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Pubblicato in:ACS Chem Neurosci
Autori principali: Martin, Tye D., Brinkley, Gabriella, Whitten, David G., Chi, Eva Y., Evans, Deborah G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7739895/
https://ncbi.nlm.nih.gov/pubmed/33141569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschemneuro.0c00360
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