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Covalent Targeting of Ras G12C by Rationally Designed Peptidomimetics
Protein-protein interactions (PPIs) play a critical role in fundamental biological processes. Competitive inhibition of these interfaces requires compounds that can access discontinuous binding epitopes along a large, shallow binding surface area. Conformationally-defined protein surface mimics pres...
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| Vydáno v: | ACS Chem Biol |
|---|---|
| Hlavní autoři: | , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2020
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7739374/ https://ncbi.nlm.nih.gov/pubmed/32378881 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.0c00204 |
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