Gut microbiota dysbiosis and altered tryptophan catabolism contribute to autoimmunity in lupus-susceptible mice

Pathogenic mechanisms involved in the autoimmune disorder systemic lupus erythematosus (SLE) remain elusive. However, dysbiosis of the gut microbiota may be involved in disease pathogenesis. We demonstrate that the dysbiotic gut microbiota of lupus-prone mice induced autoimmunity when transferred in...

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Detaylı Bibliyografya
Yayımlandı:Sci Transl Med
Asıl Yazarlar: Choi, Seung-Chul, Brown, Josephine, Gong, Minghao, Ge, Yong, Zadeh, Mojgan, Li, Wei, Croker, Byron P., Michailidis, George, Garrett, Timothy J., Mohamadzadeh, Mansour, Morel, Laurence
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2020
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7739186/
https://ncbi.nlm.nih.gov/pubmed/32641487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aax2220
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