Dysregulation of tryptophan catabolism at the host-skin microbiota interface in hidradenitis suppurativa

Hidradenitis suppurativa (HS) is a chronic skin disorder of unknown etiology that manifests as recurrent, painful lesions. Cutaneous dysbiosis and unresolved inflammation are hallmarks of active HS, but their origin and interplay remain unclear. Our metabolomic profiling of HS skin revealed an abnor...

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Bibliografiske detaljer
Udgivet i:JCI Insight
Main Authors: Guenin-Macé, Laure, Morel, Jean-David, Doisne, Jean-Marc, Schiavo, Angèle, Boulet, Lysiane, Mayau, Véronique, Goncalves, Pedro, Duchatelet, Sabine, Hovnanian, Alain, Bondet, Vincent, Duffy, Darragh, Ungeheuer, Marie-Noëlle, Delage, Maïa, Nassif, Aude, Di Santo, James P., Demangel, Caroline
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2020
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7605522/
https://ncbi.nlm.nih.gov/pubmed/32970636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.140598
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