Dysregulation of tryptophan catabolism at the host-skin microbiota interface in hidradenitis suppurativa

Hidradenitis suppurativa (HS) is a chronic skin disorder of unknown etiology that manifests as recurrent, painful lesions. Cutaneous dysbiosis and unresolved inflammation are hallmarks of active HS, but their origin and interplay remain unclear. Our metabolomic profiling of HS skin revealed an abnor...

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Dettagli Bibliografici
Pubblicato in:JCI Insight
Autori principali: Guenin-Macé, Laure, Morel, Jean-David, Doisne, Jean-Marc, Schiavo, Angèle, Boulet, Lysiane, Mayau, Véronique, Goncalves, Pedro, Duchatelet, Sabine, Hovnanian, Alain, Bondet, Vincent, Duffy, Darragh, Ungeheuer, Marie-Noëlle, Delage, Maïa, Nassif, Aude, Di Santo, James P., Demangel, Caroline
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2020
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7605522/
https://ncbi.nlm.nih.gov/pubmed/32970636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.140598
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