Dysregulation of tryptophan catabolism at the host-skin microbiota interface in hidradenitis suppurativa

Hidradenitis suppurativa (HS) is a chronic skin disorder of unknown etiology that manifests as recurrent, painful lesions. Cutaneous dysbiosis and unresolved inflammation are hallmarks of active HS, but their origin and interplay remain unclear. Our metabolomic profiling of HS skin revealed an abnor...

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發表在:JCI Insight
Main Authors: Guenin-Macé, Laure, Morel, Jean-David, Doisne, Jean-Marc, Schiavo, Angèle, Boulet, Lysiane, Mayau, Véronique, Goncalves, Pedro, Duchatelet, Sabine, Hovnanian, Alain, Bondet, Vincent, Duffy, Darragh, Ungeheuer, Marie-Noëlle, Delage, Maïa, Nassif, Aude, Di Santo, James P., Demangel, Caroline
格式: Artigo
語言:Inglês
出版: American Society for Clinical Investigation 2020
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Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7605522/
https://ncbi.nlm.nih.gov/pubmed/32970636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.140598
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