Increased methylation of NR3C1 and SLC6A4 is associated with blunted cortisol reactivity to stress in major depression

BACKGROUND: Epigenetic changes are considered the main mechanisms behind the interplay of environment and genetic susceptibility in major depressive disorder (MDD). However, studies focusing on epigenetic dysregulation of the HPA axis stress response in MDD are lacking. Our objective was to simultan...

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Detalles Bibliográficos
Publicado en:Neurobiol Stress
Main Authors: Bakusic, Jelena, Vrieze, Elske, Ghosh, Manosij, Bekaert, Bram, Claes, Stephan, Godderis, Lode
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2020
Assuntos:
Original Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7739183/
https://ncbi.nlm.nih.gov/pubmed/33344725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ynstr.2020.100272
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