Increased methylation of NR3C1 and SLC6A4 is associated with blunted cortisol reactivity to stress in major depression

BACKGROUND: Epigenetic changes are considered the main mechanisms behind the interplay of environment and genetic susceptibility in major depressive disorder (MDD). However, studies focusing on epigenetic dysregulation of the HPA axis stress response in MDD are lacking. Our objective was to simultan...

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Vydáno v:Neurobiol Stress
Hlavní autoři: Bakusic, Jelena, Vrieze, Elske, Ghosh, Manosij, Bekaert, Bram, Claes, Stephan, Godderis, Lode
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2020
Témata:
Original Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7739183/
https://ncbi.nlm.nih.gov/pubmed/33344725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ynstr.2020.100272
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