The stress susceptibility factor FKBP51 controls S-ketamine-evoked release of mBDNF in the prefrontal cortex of mice

We report here the involvement of the stress-responsive glucocorticoid receptor co-chaperone FKBP51 in the mechanism of in vivo secretion of mature BDNF (mBDNF). We used a novel method combining brain microdialysis with a capillary electrophoresis-based immunoassay, to examine mBDNF secretion in the...

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Detalhes bibliográficos
Publicado no:Neurobiol Stress
Main Authors: Anderzhanova, Elmira, Hafner, Kathrin, Genewsky, Andreas J., Soliman, Azza, Pöhlmann, Max L., Schmidt, Mathias V., Blum, Robert, Wotjak, Carsten T., Gassen, Nils C.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
Assuntos:
Original Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7739030/
https://ncbi.nlm.nih.gov/pubmed/33344695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ynstr.2020.100239
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