Putting the BRK on breast cancer: From molecular target to therapeutics

BReast tumor Kinase (BRK, also known as PTK6) is a non-receptor tyrosine kinase that is highly expressed in breast carcinomas while having low expression in the normal mammary gland, which hints at the oncogenic nature of this kinase in breast cancer. In the past twenty-six years since the discovery...

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Vydáno v:Theranostics
Hlavní autoři: Ang, Hui Li, Yuan, Yi, Lai, Xianning, Tan, Tuan Zea, Wang, Lingzhi, Huang, Benjamin BoJun, Pandey, Vijay, Huang, Ruby Yun-Ju, Lobie, Peter E., Goh, Boon Cher, Sethi, Gautam, Yap, Celestial T., Chan, Ching Wan, Lee, Soo Chin, Kumar, Alan Prem
Médium: Artigo
Jazyk:Inglês
Vydáno: Ivyspring International Publisher 2021
Témata:
Review
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7738883/
https://ncbi.nlm.nih.gov/pubmed/33391524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.49716
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