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Targeting STAT3 and oxidative phosphorylation in oncogene-addicted tumors

Drug resistance invariably limits the response of oncogene-addicted cancer cells to targeted therapy. The upregulation of signal transducer and activator of transcription 3 (STAT3) has been implicated as a mechanism of drug resistance in a range of oncogene-addicted cancers. However, the development...

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Vydáno v:Redox Biol
Hlavní autoři: Lee, Matilda, Hirpara, Jayshree L., Eu, Jie-Qing, Sethi, Gautam, Wang, Lingzhi, Goh, Boon-Cher, Wong, Andrea L.
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6859582/
https://ncbi.nlm.nih.gov/pubmed/30594485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2018.101073
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