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Integrative analysis of multi-platform reverse-phase protein array data for the pharmacodynamic assessment of response to targeted therapies

Reverse-phase protein array (RPPA) technology uses panels of high-specificity antibodies to measure proteins and protein post-translational modifications in cells and tissues. The approach offers sensitive and precise quantification of large numbers of samples and has thus found applications in the...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Byron, Adam, Bernhardt, Stephan, Ouine, Bérèngere, Cartier, Aurélie, Macleod, Kenneth G., Carragher, Neil O., Sibut, Vonick, Korf, Ulrike, Serrels, Bryan, de Koning, Leanne
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7738515/
https://ncbi.nlm.nih.gov/pubmed/33319783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-77335-0
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