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Integrating comprehensive functional annotations to boost power and accuracy in gene-based association analysis
Gene-based association tests aggregate genotypes across multiple variants for each gene, providing an interpretable gene-level analysis framework for genome-wide association studies (GWAS). Early gene-based test applications often focused on rare coding variants; a more recent wave of gene-based met...
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| Udgivet i: | PLoS Genet |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7737906/ https://ncbi.nlm.nih.gov/pubmed/33320851 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1009060 |
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