Integrating comprehensive functional annotations to boost power and accuracy in gene-based association analysis.
Gene-based association tests aggregate genotypes across multiple variants for each gene, providing an interpretable gene-level analysis framework for genome-wide association studies (GWAS). Early gene-based test applications often focused on rare coding variants; a more recent wave of gene-based met...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Public Library of Science (PLoS)
2020-12-01
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| Col·lecció: | PLoS Genetics |
| Accés en línia: | https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1009060&type=printable |
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