Nuclear lipid droplets form in the inner nuclear membrane in a seipin-independent manner

Nuclear lipid droplets (LDs) in hepatocytes are derived from precursors of very-low-density lipoprotein in the ER lumen, but it is not known how cells lacking the lipoprotein secretory function form nuclear LDs. Here, we show that the inner nuclear membrane (INM) of U2OS cells harbors triglyceride s...

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Detalhes bibliográficos
Publicado no:J Cell Biol
Main Authors: Sołtysik, Kamil, Ohsaki, Yuki, Tatematsu, Tsuyako, Cheng, Jinglei, Maeda, Asami, Morita, Shin-ya, Fujimoto, Toyoshi
Formato: Artigo
Idioma:Inglês
Publicado em: Rockefeller University Press 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7737703/
https://ncbi.nlm.nih.gov/pubmed/33315072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.202005026
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