Nuclear lipid droplets form in the inner nuclear membrane in a seipin-independent manner

Nuclear lipid droplets (LDs) in hepatocytes are derived from precursors of very-low-density lipoprotein in the ER lumen, but it is not known how cells lacking the lipoprotein secretory function form nuclear LDs. Here, we show that the inner nuclear membrane (INM) of U2OS cells harbors triglyceride s...

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Bibliografiske detaljer
Udgivet i:J Cell Biol
Main Authors: Sołtysik, Kamil, Ohsaki, Yuki, Tatematsu, Tsuyako, Cheng, Jinglei, Maeda, Asami, Morita, Shin-ya, Fujimoto, Toyoshi
Format: Artigo
Sprog:Inglês
Udgivet: Rockefeller University Press 2020
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Report
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7737703/
https://ncbi.nlm.nih.gov/pubmed/33315072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.202005026
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