Mitochondrial Safeguard: a stress response that offsets extreme fusion and protects respiratory function via flickering‐induced Oma1 activation

The connectivity of mitochondria is regulated by a balance between fusion and division. Many human diseases are associated with excessive mitochondrial connectivity due to impaired Drp1, a dynamin‐related GTPase that mediates division. Here, we report a mitochondrial stress response, named mitochond...

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Publicat a:EMBO J
Autors principals: Murata, Daisuke, Yamada, Tatsuya, Tokuyama, Takeshi, Arai, Kenta, Quirós, Pedro M, López‐Otín, Carlos, Iijima, Miho, Sesaki, Hiromi
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2020
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7737612/
https://ncbi.nlm.nih.gov/pubmed/33200421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2020105074
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