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RNA Targeting in Acute Myeloid Leukemia

[Image: see text] Nucleosides and their analogues constitute an essential family of anticancer drugs. DNA has been the presumptive target of the front-line prodrug for acute myeloid leukemia (AML), cytarabine (ara-C), since the 1980s. Here, the biomolecular targeting of ara-C was evaluated in primar...

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Detalhes bibliográficos
Publicado no:ACS Pharmacol Transl Sci
Main Authors: Messikommer, Alessandra, Seipel, Katja, Byrne, Stephen, Valk, Peter J. M., Pabst, Thomas, Luedtke, Nathan W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2020
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7737216/
https://ncbi.nlm.nih.gov/pubmed/33344899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsptsci.0c00120
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