Genetic stratification of depression by neuroticism: revisiting a diagnostic tradition

BACKGROUND: Major depressive disorder and neuroticism (Neu) share a large genetic basis. We sought to determine whether this shared basis could be decomposed to identify genetic factors that are specific to depression. METHODS: We analysed summary statistics from genome-wide association studies (GWA...

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Detalhes bibliográficos
Publicado no:Psychol Med
Main Authors: Adams, Mark J., Howard, David M., Luciano, Michelle, Clarke, Toni-Kim, Davies, Gail, Hill, W. David, Smith, Daniel, Deary, Ian J., Porteous, David J., McIntosh, Andrew M.
Formato: Artigo
Idioma:Inglês
Publicado em: Cambridge University Press 2020
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7737042/
https://ncbi.nlm.nih.gov/pubmed/31576797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1017/S0033291719002629
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