JmjC-KDMs KDM3A and KDM6B modulate radioresistance under hypoxic conditions in esophageal squamous cell carcinoma

Esophageal squamous cell carcinoma (ESCC), the most frequent esophageal cancer (EC) subtype, entails dismal prognosis. Hypoxia, a common feature of advanced ESCC, is involved in resistance to radiotherapy (RT). RT response in hypoxia might be modulated through epigenetic mechanisms, constituting nov...

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Pubblicato in:Cell Death Dis
Autori principali: Macedo-Silva, Catarina, Miranda-Gonçalves, Vera, Lameirinhas, Ana, Lencart, Joana, Pereira, Alexandre, Lobo, João, Guimarães, Rita, Martins, Ana Teresa, Henrique, Rui, Bravo, Isabel, Jerónimo, Carmen
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7736883/
https://ncbi.nlm.nih.gov/pubmed/33318475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-03279-y
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