Developmental differences in genome replication program and origin activation

To ensure error-free duplication of all (epi)genetic information once per cell cycle, DNA replication follows a cell type and developmental stage specific spatio-temporal program. Here, we analyze the spatio-temporal DNA replication progression in (un)differentiated mouse embryonic stem (mES) cells....

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Detalles Bibliográficos
Publicado en:Nucleic Acids Res
Autores principales: Rausch, Cathia, Weber, Patrick, Prorok, Paulina, Hörl, David, Maiser, Andreas, Lehmkuhl, Anne, Chagin, Vadim O, Casas-Delucchi, Corella S, Leonhardt, Heinrich, Cardoso, M Cristina
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2020
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7736824/
https://ncbi.nlm.nih.gov/pubmed/33264404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa1124
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