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BCCIP is required for nucleolar recruitment of eIF6 and 12S pre-rRNA production during 60S ribosome biogenesis

Ribosome biogenesis is a fundamental process required for cell proliferation. Although evolutionally conserved, the mammalian ribosome assembly system is more complex than in yeasts. BCCIP was originally identified as a BRCA2 and p21 interacting protein. A partial loss of BCCIP function was sufficie...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Ye, Caiyong, Liu, Bochao, Lu, Huimei, Liu, Jingmei, Rabson, Arnold B, Jacinto, Estela, Pestov, Dimitri G, Shen, Zhiyuan
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7736804/
https://ncbi.nlm.nih.gov/pubmed/33245766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa1114
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