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The function of RAD52 N-terminal domain is essential for viability of BRCA-deficient cells
RAD52 is a member of the homologous recombination pathway that is important for survival of BRCA-deficient cells. Inhibition of RAD52 leads to lethality in BRCA-deficient cells. However, the exact mechanism of how RAD52 contributes to viability of BRCA-deficient cells remains unknown. Two major acti...
Shranjeno v:
| izdano v: | Nucleic Acids Res |
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| Main Authors: | , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Oxford University Press
2020
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7736796/ https://ncbi.nlm.nih.gov/pubmed/33275133 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa1145 |
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