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Identification of a differentiation stall in epithelial mesenchymal transition in histone H3–mutant diffuse midline glioma
BACKGROUND: Diffuse midline gliomas with histone H3 K27M (H3K27M) mutations occur in early childhood and are marked by an invasive phenotype and global decrease in H3K27me3, an epigenetic mark that regulates differentiation and development. H3K27M mutation timing and effect on early embryonic brain...
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| Publié dans: | Gigascience |
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| Auteurs principaux: | , , , , , , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Oxford University Press
2020
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7736793/ https://ncbi.nlm.nih.gov/pubmed/33319914 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gigascience/giaa136 |
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