Genome-wide mapping of SARS-CoV-2 RNA structures identifies therapeutically-relevant elements

SARS-CoV-2 is a betacoronavirus with a linear single-stranded, positive-sense RNA genome, whose outbreak caused the ongoing COVID-19 pandemic. The ability of coronaviruses to rapidly evolve, adapt, and cross species barriers makes the development of effective and durable therapeutic strategies a cha...

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Bibliographic Details
Published in:Nucleic Acids Res
Main Authors: Manfredonia, Ilaria, Nithin, Chandran, Ponce-Salvatierra, Almudena, Ghosh, Pritha, Wirecki, Tomasz K, Marinus, Tycho, Ogando, Natacha S, Snijder, Eric J, van Hemert, Martijn J, Bujnicki, Janusz M, Incarnato, Danny
Format: Artigo
Language:Inglês
Published: Oxford University Press 2020
Subjects:
NAR Breakthrough Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7736786/
https://ncbi.nlm.nih.gov/pubmed/33166999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa1053
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