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Senescent Cell Depletion Through Targeting BCL-Family Proteins and Mitochondria
Senescent cells with replicative arrest can be generated during genotoxic, oxidative, and oncogenic stress. Long-term retention of senescent cells in the body, which is attributed to highly expressed BCL-family proteins, chronically damages tissues mainly through a senescence-associated secretory ph...
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| 出版年: | Front Physiol |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Frontiers Media S.A.
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7736607/ https://ncbi.nlm.nih.gov/pubmed/33335487 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2020.593630 |
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