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Senescent Cell Depletion Through Targeting BCL-Family Proteins and Mitochondria

Senescent cells with replicative arrest can be generated during genotoxic, oxidative, and oncogenic stress. Long-term retention of senescent cells in the body, which is attributed to highly expressed BCL-family proteins, chronically damages tissues mainly through a senescence-associated secretory ph...

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Vydáno v:Front Physiol
Hlavní autoři: Fan, Ying, Cheng, Jiaoqi, Zeng, Huihong, Shao, Lijian
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7736607/
https://ncbi.nlm.nih.gov/pubmed/33335487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2020.593630
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