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Non-opioid, GTS-21 Mitigates Burn Injury Pain in Rats by Decreasing Spinal Cord Inflammatory Responses
BACKGROUND: Burn injury (BI) pain consists of inflammatory and neuropathic components and activates microglia. Nicotinic α7acetylcholine receptors (α7AChRs) expressed in microglia exhibit immuno-modulatory activity during agonist stimulation. Efficacy of selective α7AChR agonist, GTS-21 to mitigate...
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| Publicado en: | Anesth Analg |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2021
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7736563/ https://ncbi.nlm.nih.gov/pubmed/33264122 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1213/ANE.0000000000005274 |
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