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Myristoylation of EV71 VP4 is Essential for Infectivity and Interaction with Membrane Structure

The Enterovirus 71 (EV71) VP4 is co-translationally linked to myristic acid at its amino-terminal glycine residue. However, the role of this myristoylation in the EV71 life cycle remains largely unknown. To investigate this issue, we developed a myristoylation-deficient virus and reporter (luciferas...

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Detalhes bibliográficos
Publicado no:Virol Sin
Main Authors: Cao, Jiaming, Qu, Meng, Liu, Hongtao, Wan, Xuan, Li, Fang, Hou, Ali, Zhou, Yan, Sun, Bo, Cai, Linjun, Su, Weiheng, Jiang, Chunlai
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Singapore 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7736455/
https://ncbi.nlm.nih.gov/pubmed/32399947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12250-020-00226-1
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