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Identification of specific antigenic epitope at N-terminal segment of enterovirus 71 (EV-71) VP1 protein and characterization of its use in recombinant form for early diagnosis of EV-71 infection

Human enterovirus 71 (EV-71) is the main etiologic agent of hand, foot and mouth disease (HFMD). We sought to identify EV-71 specific antigens and develop serologic assays for acute-phase EV-71 infection. A series of truncated proteins within the N-terminal 100 amino acids (aa) of EV-71 VP1 was expr...

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Detalhes bibliográficos
Publicado no:Virus Res
Main Authors: Zhang, Jianhua, Jiang, Bingfu, Xu, Mingjie, Dai, Xing, Purdy, Michael A., Meng, Jihong
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4698801/
https://ncbi.nlm.nih.gov/pubmed/24952304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virusres.2014.06.003
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