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An autoregulatory feedback loop of miR-21/VMP1 is responsible for the abnormal expression of miR-21 in colorectal cancer cells

MircoRNA-21 (miR-21) was found to be highly expressed in various solid tumors, and its oncogenic properties have been extensively studied in recent years. However, the reason why miR-21 is highly expressed in various tumors remains elusive. Here, we found that the expression of miR-21 was negatively...

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Détails bibliographiques
Publié dans:Cell Death Dis
Auteurs principaux: Wang, Caixia, Peng, Rui, Zeng, Min, Zhang, Zhenhua, Liu, Shengpeng, Jiang, Dan, Lu, Yuanyuan, Zou, Fangdong
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7736343/
https://ncbi.nlm.nih.gov/pubmed/33318473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-03265-4
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