CASK modulates the assembly and function of the Mint1/Munc18-1 complex to regulate insulin secretion

Calcium/calmodulin-dependent protein serine kinase (CASK) is a key player in vesicle transport and release in neurons. However, its precise role, particularly in nonneuronal systems, is incompletely understood. We report that CASK functions as an important regulator of insulin secretion. CASK deplet...

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Detalhes bibliográficos
Publicado no:Cell Discov
Main Authors: Zhang, Zhe, Li, Wei, Yang, Guang, Lu, Xuefeng, Qi, Xin, Wang, Shuting, Cao, Can, Zhang, Peng, Ren, Jinqi, Zhao, Jiaxu, Zhang, Junyi, Hong, Sheng, Tan, Yan, Burchfield, James, Yu, Yang, Xu, Tao, Yao, Xuebiao, James, David, Feng, Wei, Chen, Zhengjun
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Singapore 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7736295/
https://ncbi.nlm.nih.gov/pubmed/33318489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41421-020-00216-3
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