BRD4 Interacts with GATA4 to Govern Mitochondrial Homeostasis in Adult Cardiomyocytes

BACKGROUND: Gene regulatory networks control tissue homeostasis and disease progression in a cell-type specific manner. Ubiquitously expressed chromatin regulators modulate these networks, yet the mechanisms governing how tissue-specificity of their function is achieved are poorly understood. BRD4,...

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Pubblicato in:Circulation
Autori principali: Padmanabhan, Arun, Alexanian, Michael, Linares-Saldana, Ricardo, González-Terán, Bárbara, Andreoletti, Gaia, Huang, Yu, Connolly, Andrew J., Kim, Wonho, Hsu, Austin, Duan, Qiming, Winchester, Sarah A. B., Felix, Franco, Perez-Bermejo, Juan A., Wang, Qiaohong, Li, Li, Shah, Parisha P., Haldar, Saptarsi M., Jain, Rajan, Srivastava, Deepak
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7736290/
https://ncbi.nlm.nih.gov/pubmed/33094644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.120.047753
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